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That is why the main product used for vulvodynia is a low-dose estrogen vaginal cream used externally (outside of the vagina). alternatively, lie on your back with your knees bent and your feet apart. Separate the lips of your vulva and gently insert the applicator. If you start menstruating while using vaginal cream, keep applying it. However, you should use sanitary pads, since tampons can absorb the cream. Estrogen is a hormone that can help ease certain vaginal problems like dryness or urinary issues, especially those associated with the menopause. The cream typically works best when the woman applies it inside the vagina, and the estrogen cream usually comes with an applicator. vaginal estrogen cream is used to treat the above-mentioned symptoms, as well as others. If you have any of the above symptoms and are going through menopause, talk to your doctor. They may want to run a few tests before prescribing a vaginal cream to help alleviate these symptoms. vulva irritation usually refers to pain, itching, or swelling in the vaginal area. Applying an otc hydrocortisone cream to help with itching, irritation, and redness. And then when you apply estrogen cream, the medium its mixed in may get into the tiny cracks and make things worse. (for estrogen to be absorbable, it has to be whipped into a gel or cream that you then apply to your skin.). Safety and efficacy of bedtime versus daytime administration of the miconazole nitrate 1200 mg vaginal ovule insert to treat vulvovaginal candidiasis. Chase dj, schenkel bp, fahr am, eigner u tampon study group. A little quick history, i am a nurse too but need a little more info. I am 2 years out from diagnosis from estrogen positive breast cancer. Applying estriol to the vaginal tissues can be very helpful for vaginal atrophy, vaginal dryness or pain with intercourse from menopause or lack of estrogen. estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy.