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Nuclear medicine breast imaging is not a screening tool for breast cancer. However, after a physical breast exam, mammography, and ultrasound are performed, nuclear medicine breast imaging may be appropriate for certain patients. Supplemental breast imaging helps determine whether a patient has a suspicious breast abnormality that would require a biopsy to confirm the presence of breast cancer. nuclear medicine offers many diagnostic tools for the primary detection, staging, and evaluation of treatment response in breast cancer. The recent developments in breast imaging have been achieved include a diversity of breast imaging modalities, including whole-body pet systems. Breast cancer starts in the breast cells of both women and men. Worldwide, breast cancer is the second most common type of cancer after lung cancer (10. 9 of cancer incidence in both men and women) and the fifth most common cause of cancer death. Bombardieri e(1), crippa f, baio sm, peeters ba, greco m, pauwels ek. Author information (1)division of nuclear medicine, istituto nazionale per lo studio e la cura dei tumori, milan, italy. It primary breast cancer imaging can be done by various means. nuclear medicine advances in breast cancer imaging tumori journal, vol. Scintimammography can detect breast cancer even when dense breast tissue or breast implants are present. Because only a small dose of radiotracer is used, nuclear medicine exams have a relatively low radiation exposure. Thus, the radiation risk is very low when compared with the potential benefits. the main difference between nuclear imaging and ct scans is that nuclear imaging assesses how organs function and ct scans assess how organs look. From 2000 to 2010, use of ct scans increased dramatically, and a study suggests that more ct scans may lead to a higher risk of breast cancer in women, especially young women who have repeat scans. Breast cancer forms in tissues of the breastusually in the ducts, tubes that carry milk to the nipple, and lobules, the glands that make milk. It occurs in both men and women, although male breast cancer is rare. According to estimates by the american cancer society, more than 279,000 people in the united states will be diagnosed with breast cancer and nearly 42,000 people will die from the.